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IGM Faculty

Kelly A. Frazer, Ph.D.

Director, Institute for Genomic Medicine
Professor of Pediatrics

Disease predisposition in cancer, congenital heart disease, asthma, and obesity, using genomic information. Next generation sequencing platforms.

Bruce Hamilton, Ph.D.

Professor of Cellular & Molecular Medicine
Professor of Medicine
Director, UCSD Genetics Training Program
Associate Director, IGM

Genetic architectures and modifier genes. Transcriptional and post-transcriptional regulatory networks in brain development and disease.

Susan Ackerman, Ph.D.

Professor of Cellular & Molecular Medicine and Steven Kuffler Chair of Biology (Neurobiology)
Howards Hughes Medical Institute Investigator

Genetic mechanisms of neurodevelopment and neurodegeneration, post-transcriptional regulation of neuronal homeostasis.

Ludmil Alexandrov, Ph.D.

Assistant Professor of Cellular and Molecular Medicine and Bioengineering

We leverage machine learning approaches to understand the processes that cause cancer and identify strategies for cancer treatment and cancer prevention.

Vineet Bafna, Ph.D.

Professor of Computer Science

My research interest is Bioinformatics.

Chris Benner, Ph.D.

Assistant Professor of Medicine, Division of Endocrinology

Transcriptional regulation and regulatory element analysis in a wide range of systems, with an emphasis on infectious disease.

Hannah Carter, Ph.D.

Assistant Professor of Medicine
Division of Genetics

Stephanie Cherqui, Ph.D.

Associate Professor of Pediatrics, Division of Genetics

Development of preclinical and clinical stem cell and gene therapy approaches for genetic disorders.

Neil Chi, Ph.D.

Associate Professor of Medicine
Director, UCSD Cardiovascular Genetics Clinic and Cardiac Tissue Harvest and Biorepository Core

Farley

Emma Farley, Ph.D.

Assistant Professor of Medicine and Molecular Biology

We use high-throughput functional approaches within developing embryos to decipher how enhancers encode the instructions for successful development and to pinpoint enhancer mutations associated with disease.

Xiang-Dong Fu, Ph.D.

Professor of Cellular & Molecular Medicine

Nuclear architectures for regulated gene expression, coupling between transcription and splicing, and genomics of RNA binding proteins. Applications to heart remodeling, breast and prostate cancer.

Frank Furnari, Ph.D.

Professor of Pathology

Identifying and targeting genetic and epigenetic mechanisms that cause adult and pediatric brain tumors

Terry Gaasterland, Ph.D.

Professor of Computational Biology and Genomics
Director, Scripps Genome Center

Computational methods to analyze large-scale and high-dimensional genome-wide data. Assembly and annotation of model organism genomes. Genomics of Primary Open Angle Glaucoma, young onset Alzheimer's, and Prostate Cancer Bone Metastasis.

Kyle Gaulton, Ph.D.

Assistant Professor of Pediatrics

Christopher K. Glass, M.D., Ph.D.

Professor of Medicine and Cellular & Molecular Medicine

Transcriptional regulation of the macrophage in immunity and inflammatory disease.

Joe Gleeson, M.D.

Professor of Neurosciences
Investigator of the Howard Hughes Medical Institute
Rady Children’s Genomic Medicine

Computational and cell biological approaches to genetic forms of pediatric brain disease.

Alon Goren, Ph.D.

Assistant Professor of Medicine

Employment of molecular biology, technological innovations and computational analyses to study epigenomic mechanisms.

Gymrek

Melissa Gymrek, Ph.D.

Assistant Professor of Medicine and Computer Science and Engineering

The role of repetitive genetic variation in human disease

Sven Heinz, Ph.D.

Assistant Professor In Residence of Medicine

Transcription regulation and genome 3D structure in inflammatory stimulus responses, virus infections and cancer. Method development and repurposing chromatin profiling methods for clinical diagnostics.

Trey Ideker, Ph.D.

Professor of Bioengineering and Medicine

Network and systems biology, high-throughput enabling technologies.

John Kelsoe, M.D.

Professor of Psychiatry

Psychiatric genetics, especially bipolar disorder and schizophrenia.

Richard Kolodner, Ph.D.

Professor of Medicine
Executive Director for Laboratory Science & Technology, New York Office–Ludwig Institute for Cancer Research
Head, Laboratory of Cancer Genetics, San Diego Branch–Ludwig Institute for Cancer Research

Genome stability, maintenance and repair in model systems and human cancers.

Louise Laurent, M.D., Ph.D.

Professor of Obstetrics, Gynecology, and Reproductive Sciences

Our research focuses on understanding how cell identity is determined and how transitions between cells states are regulated, both in normal development and in disease. We combine expertise in stem cell biology and genomics to tackle problems in basic developmental biology, focusing on the placenta, as well as translational targets, such as discovery of biomarkers predictive or diagnostic of preterm birth, preeclampsia, and other disorders of placentation.

Prashant Mali, Ph.D.

Assistant Professor of Bioengineering

Genome Engineering, Synthetic Biology, Regenerative Medicine

Amit R. Majithia, MD

Assistant Professor of Medicine and Pediatrics
Division of Endocrinology

Integrative functional genomic and human genetic approach to discovering cardiometabolic disease genes with therapeutic properties.

Jill P. Mesirov, Ph.D.

Associate Vice Chancellor for Computational Health Sciences
Professor of Medicine
Moores Cancer Center

Machine learning and statistical methods for analysis of genomic data with particular emphasis on applications to cancer genomics and infectious disease. Development and dissemination of open source software tools embodying the computational methods.

Alysson R. Muotri, Ph.D.

University of California San Diego, School of Medicine
Professor of Pediatrics
Professor of Cellular & Molecular Medicine
Director of the UCSD Stem Cell Program
UCSD Moore’s Cancer Center

Applying molecular tools and stem cells models to understand brain development, complexity and evolution.

Abraham Palmer, Ph.D.

Professor and Vice Chair for Basic Research, Department of Psychiatry

Genome wide association in mice, rats and humans; integration of behavioral, physiological and gene expression traits.

Tariq Rana, Ph.D.

Professor of Pediatrics, V/C for Innovation in Therapeutics

AIDS, immune disorders, neurodegenerative diseases, and cancer

Bing Ren, Ph.D.

Professor of Cellular & Molecular Medicine

Epigenetics, genome-wide expression and high-throughput technologies to identify genomic architectures of expression states in cancer and normal cells.

Maike Sander, M.D.

Professor of Pediatrics and Cellular & Molecular Medicine

Jonathan Sebat, Ph.D.

Professor of Psychiatry and Cellular & Molecular Medicine
Chief, Beyster Center for Molecular Genomics of Neuropsychiatric Diseases

Genetics of neuropsychiatric disorders. The role of structural variation, including copy number variants (CNVs), in disease.

Xin Sun, Ph.D.

Professor of Pediatrics

Ming T. Tsuang, M.D., Ph.D., D.Sc.

University Professor, University of California
Lewis Judd Endowed Chair in Behavioral Genomic
Distinguished Professor of Psychiatry
Director, Center for Behavioral Genomics
Department of Psychiatry

Interactions between genetic and environmental risk factors for severe mental disorders.

Miles Wilkinson, Ph.D.

Professor of Obstetrics, Gynecology, and Reproductive Sciences

Transcriptional regulatory pathways in stem cell and germ cell development; Biological functions of nonsense-mediated RNA decay (NMD), a conserved and selective RNA turnover pathway that functions in early embryonic development, neural development, and neural functions.

Elizabeth Winzeler, Ph.D.

Professor of Pediatrics
Director of Translational Research, UC Health Sciences Center for Immunology, Infection and Inflammation

Genetics, genomics, sequencing, microarrays, chemical genetics, drug discovery, bio and cheminformatics in neglected/infected diseases.

Gene Yeo, Ph.D., M.B.A.

Professor of Cellular & Molecular Medicine
Co-Director Bioinformatics and Systems Biology Graduate Program
Member, UCSD Stem Cell Program
Member, Moores Cancer Center
Department of Bioengineering (Adjunct)
Neurosciences Graduate Program (Adjunct)

Post-transcriptional regulation by RNA binding proteins in neurological and mental disorders, virus-host interactions and cancer.

Kun Zhang, Ph.D.

Chair of the Department of Bioengineering
Professor of Bioengineering

Genomic technologies, including single-molecule sequencing, single-cell manipulations and chip-based synthetic strategies. Applications in stem cell biology, microbiome, personal genomes, and common human disorders.

Sheng Zhong, Ph.D.

Professor of Bioengineering

Computational genomics, stem cell engineering, molecular biotechnologies