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IGM Faculty

Kelly A. Frazer, Ph.D.

Director, Institute for Genomic Medicine
Professor of Pediatrics

Disease predisposition in cancer, congenital heart disease, asthma, and obesity, using genomic information. Next generation sequencing platforms.

Bruce Hamilton, Ph.D.

Professor of Cellular and Molecular Medicine
Professor of Medicine
Director, UCSD Genetics Training Program
Associate Director, IGM

Genetic architectures and modifier genes. Transcriptional and post-transcriptional regulatory networks in brain development and disease.

Al La Spada, M.D., Ph.D.

Professor of Pediatrics and Cellular and Molecular Medicine
Associate Director, IGM

Mechanisms of neural development and neurodegenerative disease; Development of therapies for neurological disorders.

Susan Ackerman, Ph.D.

Professor of Cellular and Molecular Medicine and Steven Kuffler Chair of Biology (Neurobiology)
Howards Hughes Medical Institute Investigator

Genetic mechanisms of neurodevelopment and neurodegeneration, post-transcriptional regulation of neuronal homeostasis.

Vineet Bafna, Ph.D.

Professor of Computer Science

My research interest is Bioinformatics.

Hannah Carter, Ph.D.

Assistant Professor of Medicine
Division of Genetics

Neil Chi, Ph.D.

Associate Professor of Medicine
Director, UCSD Cardiovascular Genetics Clinic and Cardiac Tissue Harvest and Biorepository Core

Farley

Emma Farley, Ph.D.

Assistant Professor of Medicine and Molecular Biology

We use high-throughput functional approaches within developing embryos to decipher how enhancers encode the instructions for successful development and to pinpoint enhancer mutations associated with disease.

Xiang-Dong Fu, Ph.D.

Professor of Cellular and Molecular Medicine

Nuclear architectures for regulated gene expression, coupling between transcription and splicing, and genomics of RNA binding proteins. Applications to heart remodeling, breast and prostate cancer.

Theodore "Ted" Friedmann, A.B., M.D.

Professor of Pediatrics

Lesch Nyhan Disease, Alzheimer's

Terry Gaasterland, Ph.D.

Professor of Computational Biology and Genomics
Director, Scripps Genome Center

Computational methods to analyze large-scale and high-dimensional genome-wide data. Assembly and annotation of model organism genomes.

Kyle Gaulton, Ph.D.

Assistant Professor of Pediatrics

Christopher K. Glass, M.D., Ph.D.

Professor of Medicine and Cellular and Molecular Medicine

Transcriptional regulation of the macrophage in immunity and inflammatory disease.

Joe Gleeson, M.D.

Professor of Neurosciences
Investigator of the Howard Hughes Medical Institute
Rady Children’s Genomic Medicine

Computational and cell biological approaches to genetic forms of pediatric brain disease.

Alon Goren, Ph.D.

Assistant Professor of Medicine

Gymrek

Melissa Gymrek, Ph.D.

Assistant Professor of Medicine and Computer Science and Engineering

The role of repetitive genetic variation in human disease

Trey Ideker, Ph.D.

Division Chief, Medical Genetics
Professor of Bioengineering and Medicine

Network and systems biology, high-throughput enabling technologies.

John Kelsoe, M.D.

Professor of Psychiatry

Psychiatric genetics, especially bipolar disorder and schizophrenia.

Richard Kolodner, Ph.D.

Professor of Medicine
Executive Director for Laboratory Science & Technology, New York Office–Ludwig Institute for Cancer Research
Head, Laboratory of Cancer Genetics, San Diego Branch–Ludwig Institute for Cancer Research

Genome stability, maintenance and repair in model systems and human cancers.

Prashant Mali, Ph.D.

Assistant Professor of Bioengineering

Genome Engineering, Synthetic Biology, Regenerative Medicine

Jill P. Mesirov, Ph.D.

Associate Vice Chancellor for Computational Health Sciences
Professor of Medicine
Moores Cancer Center

Machine learning and statistical methods for analysis of genomic data with particular emphasis on applications to cancer genomics and infectious disease. Development and dissemination of open source software tools embodying the computational methods.

Alysson Muotri, Ph.D.

Associate Professor Pediatrics, Cellular and Molecular Medicine

Applying molecular tools and stem cells models to understand brain development, complexity and evolution.

Tariq Rana, Ph.D.

Professor of Pediatrics, V/C for Innovation in Therapeutics

AIDS, immune disorders, neurodegenerative diseases, and cancer

Bing Ren, Ph.D.

Professor of Cellular and Molecular Medicine

Epigenetics, genome-wide expression and high-throughput technologies to identify genomic architectures of expression states in cancer and normal cells.

Abraham Palmer, Ph.D.

Professor and Vice Chair for Basic Research, Department of Psychiatry

Genome wide association in mice, rats and humans; integration of behavioral, physiological and gene expression traits.

Maike Sander, M.D.

Professor of Pediatrics and Cellular & Molecular Medicine

Jonathan Sebat, Ph.D.

Professor of Psychiatry and Cellular and Molecular Medicine
Chief, Beyster Center for Molecular Genomics of Neuropsychiatric Diseases

Genetics of neuropsychiatric disorders. The role of structural variation, including copy number variants (CNVs), in disease.

Ming T. Tsuang, M.D., Ph.D., D.Sc.

Behavioral Genomics Endowed Chair and Distinguished University Professor
Director, Center for Behavioral Genomics
Department of Psychiatry

Interactions between genetic and environmental risk factors for severe mental disorders.

Miles Wilkinson, Ph.D.

Professor of Reproductive Medicine

Transcriptional regulatory pathways in stem cell and germ cell development; RNA surveillance and quality-control mechanisms in developmental defects and cancer.

Elizabeth Winzeler, Ph.D.

Professor of Pediatrics
Director of Translational Research, UC Health Sciences Center for Immunology, Infection and Inflammation

Genetics, genomics, sequencing, microarrays, chemical genetics, drug discovery, bio and cheminformatics in neglected/infected diseases.

Gene Yeo, Ph.D.

Associate Professor of Cellular and Molecular Medicine

Post-transcriptional regulation by RNA binding proteins in neurological and mental disorders, virus-host interactions and cancer.

Kang Zhang, M.D., Ph.D.

Professor of Ophthalmology
Shiley Eye Institute
Chief, Ophthalmic Genetics

Genetic mechanisms in retinal diseases, including macular degeneration, retinitis pigmentosa and glaucoma.

Kun Zhang, Ph.D.

Assistant Professor of Bioengineering

Genomic technologies, including single-molecule sequencing, single-cell manipulations and chip-based synthetic strategies. Applications in stem cell biology, microbiome, personal genomes, and common human disorders.

Sheng Zhong, Ph.D.

Associate Professor of Bioengineering

Computational genomics, stem cell engineering, molecular biotechnologies