Institute for Genomic Medicine

IGM Faculty

Vineet Bafna, PhD.

Professor of Computer Science

My research interest is Bioinformatics.

Neil Chi, PhD.

Kelly A. Frazer, Ph.D.

Professor of Pediatrics

Disease predisposition in cancer, congenital heart disease, asthma, and obesity, using genomic information. Next generation sequencing platforms.

Xiang-Dong Fu, Ph.D.

Professor of Cellular and Molecular Medicine

Nuclear architectures for regulated gene expression, coupling between transcription and splicing, and genomics of RNA binding proteins.  Applications to heart remodeling, breast and prostate cancer.

Terry Gaasterland, Ph.D.

Professor of Computational Biology and Genomics; Director, Scripps Genome Center

Computational methods to analyze large-scale and high-dimensional genome-wide data. Assembly and annotation of model organism genomes.

Christopher K. Glass, M.D., Ph.D.

Professor of Medicine and Cellular and Molecular Medicine

Transcriptional regulation of the macrophage in immunity and inflammatory disease.

Joe Gleeson, M.D.

Professor of Neurosciences
Investigator of the Howard Hughes Medical Institute

Clinical neurology, human genetics and genomics.

Bruce Hamilton, Ph.D.

Professor of Medicine, Professor of Cellular and Molecular Medicine, and Director, UCSD Genetics Training Program
Associate Director, IGM

Genetic architectures and modifier genes. Transcriptional and post-transcriptional regulatory networks in brain development and disease.

Trey Ideker, Ph.D.

Division Chief, Medical Genetics,
Professor of Bioengineering and Medicine

Network and systems biology, high-throughput enabling technologies.

John Kelsoe, M.D.

Professor of Psychiatry

Psychiatric genetics, especially bipolar disorder and schizophrenia.

Richard Kolodner, Ph.D.

Professor of Medicine
Executive Director for Laboratory Science & Technology, New York Office- Ludwig Institute for Cancer Research
Head, Laboratory of Cancer Genetics, San Diego Branch-Ludwig Institute for Cancer Research

Genome stability, maintenance and repair in model systems and human cancers.

Al La Spada, M.D., Ph.D.

Professor of Pediatrics and Cellular and Molecular Medicine
Associate Director, IGM

Mechanisms of neural development and neurodegenerative disease; Development of therapies for neurological disorders.

Alysson Muotri, Ph.D.

Daniel T. O’Connor, M.D.

Professor of Medicine and Pharmacology

Complex human cardiovascular and renal traits, such as hypertension, renal disease, heritable responses to environmental stress, and antihypertensive drug responses.

Bing Ren, Ph.D.

Professor of Cellular and Molecular Medicine

Epigenetics, genome-wide expression and high-throughput technologies to identify genomic architectures of expression states in cancer and normal cells.

Jonathan Sebat, Ph.D.

Professor of Psychiatry and Cellular and Molecular Medicine
Chief, Beyster Center for Molecular Genomics of Neuropsychiatric Diseases

Genetics of neuropsychiatric disorders. The role of structural variation, including copy number variants (CNVs), in disease.

Ming T. Tsuang, MD, PhD, D.Sc.

Behavioral Genomics Endowed Chair and
Distinguished University Professor,
Director, Center for Behavioral Genomics,
Department of Psychiatry.

Interactions between genetic and environmental risk factors for severe mental disorders.

Miles Wilkinson, Ph.D.

Professor of Reproductive Medicine

Transcriptional regulatory pathways in stem cell and germ cell development; RNA surveillance and quality-control mechanisms in developmental defects and cancer.

Elizabeth Winzeler, PhD.

Professor of Pedaitrics

Director of Translational Research, UC Health Sciences Center for Immunology, Infection and Inflammation

Genetics, genomics, sequencing, microarrays, chemical genetics, drug discovery, bio and cheminformatics in neglected/infected diseases

 

 

Gene Yeo, Ph.D.

Assistant Professor of Cellular and Molecular Medicine

 

Post-transcriptional regulation by RNA binding proteins in neurological and mental disorders, virus-host interactions and cancer.

Benjamin D. Yu, M.D., Ph.D.

Assistant Professor in Medicine and Dermatology

Molecular, genetic and genomic approaches to phenotypic variation in the normal human population, in skin cancer and in rare diseases such as RAS/MAPK syndromes.

Kang Zhang, M.D., Ph.D.

Professor of Opthalmology, Shiley Eye Center
Retina Specialist and Human Genetics
Director, IGM

Genetic mechanisms in retinal diseases, including macular degeneration, retinitis pigmentosa and glaucoma.

Kun Zhang, Ph.D.

Assistant Professor of Bioengineering

Genomic technologies, including single-molecule sequencing, single-cell manipulations and chip-based synthetic strategies. Applications in stem cell biology, microbiome, personal genomes, and common human disorders.