Institute for Genomic Medicine

Bruce Hamilton, Ph.D.

Professor of Medicine, Professor of Cellular and Molecular Medicine, and Director, UCSD Genetics Training Program
Associate Director, IGM

Website: The Hamilton Lab
Email: bah@ucsd.edu

Pathways/processes: Neural development, Developmental signaling, Transcription, RNA export
Teams/collaborations: Cancer Center, Graduate education, Daniel O'Connor, Xiang-Dong Fu, Joe Gleeson, Gene Yeo
Approaches: Linkage, association, modifier genes, expression profiling, animal models, deep sequencing
Diseases: Hypertension, ataxias, tremor, developmental abnormalities

Research

We are interested in genetic architectures and genomic responses in brain development, neurological disorders, and neural control of blood pressure regulation.  Recent work has focused on modifier genes and gene networks in mouse models, with particular emphasis on therapeutic range in genetic titration experiments.