External Resources:

John Kelsoe, M.D.

Professor of Psychiatry

Website: https://profiles.ucsd.edu/j ohn.kelsoe
Email: jkelsoe@ucsd.edu

Pathways/processes: BioGEM, VA Genechip
Teams/collaborations: Christopher Glass, Bruce Hamilton
Approaches: Linkage, association, genome-wide expression studies
Diseases: Bipolar disorder, schizophrenia


The lab's primary focus is bipolar disorder. We conduct both clinical and molecular studies primarily directed at finding genes involved in susceptibility to bipolar disorder. We recently identified the gene for GRK3 on chromosome 22q to be a gene for bipolar disorder. Further functional and genetic studies of this gene are a major focus for the lab. We are studying many other chromosomal regions, animal models, candidate genes and clinical treatment response projects. To learn more about them, click here.