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Miles Wilkinson, Ph.D.
Professor of Reproductive Medicine
Pathways/processes: Transcription, epigenetics (DNA methylation and histone modifications), RNA splicing, RNA stability, NMD RNA surveillance pathway
Our laboratory primarily works on two topics: (1) transcriptional regulatory pathways that control embryonic stem cell and germ cell development in vivo, and (2) RNA surveillance pathways that serve as quality-control mechanisms to degrade or "correct" aberrant transcripts that would otherwise express truncated proteins causing developmental defects and/or cancer.