External Resources:

Miles Wilkinson, Ph.D.

Professor of Obstetrics, Gynecology, and Reproductive Sciences

Website: http://repromed.ucsd.edu/divisions/endocrinology/wilkinson_000.shtml
Email: mfwilkinson@ucsd.edu

Pathways/processes: Transcription, epigenetics (DNA methylation and histone modifications), RNA splicing, RNA stability, NMD RNA surveillance pathway
Teams/collaborations: n/a
Approaches: KO and KD mice, genome-wide gene expression, reproductive organs, stem cells, neural progenitors
Diseases: X-linked mental retardation, diseases caused by nonsense and frameshift mutations

Research

Transcriptional regulatory pathways in stem cell and germ cell development; Biological functions of nonsense-mediated RNA decay (NMD), a conserved and selective RNA turnover pathway that functions in early embryonic development, neural development, and neural functions.